Research Scientist, Bioanalysis

London, Greater London, England, United Kingdom

Company introduction:


Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, and has offices in New York City and San Francisco in the US. We focus on developing innovations that can improve the lives of those who are suffering with mental health challenges and who are not helped by current treatments.

 

We are pioneering the development of a new model of psilocybin treatment, in which our proprietary formulation of synthetic psilocybin (which has received breakthrough therapy designation from the FDA) is administered with psychological support. We are currently in phase 3 study for treatment-resistant depression (TRD), and phase 2 for both post-traumatic stress disorder and anorexia nervosa. Our vision is a world of mental wellbeing - Compass Pathways.


Job overview:


Join our team as a Research Scientist in Bioanalysis, where you'll contribute your expertise to our cross-functional drug discovery and development projects. With a focus on developing and validating bioanalysis methods, providing scientific oversight to drug discovery projects, and collaborating with internal stakeholders, you'll play a key role in advancing our drug development programmes. If you're ready to make a significant impact in the field of bioanalysis, we invite you to apply for this exciting opportunity.


Location: Home based in the United Kingdom (or hybrid/office based in our London office). 


Reporting: Director, Preclinical ADME.


Role and Responsibilities:


  • Serve as the bioanalytical subject matter expert on cross-functional drug discovery and development project teams
  • Manage outsourced study activities with CROs, including contracting and test item logistics, to ensure timely delivery of data and reports
  • Provide scientific and quality oversight of CROs to facilitate the development, validation and transfer of bioanalytical methods to support GxP studies
  • Work with internal stakeholders (e.g., ADME, Toxicology, Clinical Pharmacology) to build bioanalysis plans for drug development programmes
  • Keep up to date with the latest regulatory requirements and opinions in the bioanalysis field
  • Communicate to the Director, Preclinical ADME about risks, issues and possible mitigation (planned and unforeseen) of bioanalytical studies
  • Present and discuss data to internal and external collaborators
  • Oversee (with the support of the Principal Research Scientist, Bioanalysis) all aspects of regulatory enabling studies from study design, study plan/phase plan generation, method development and validation and sample analysis, through to report review and finalisation (including SEND and CTD submission) for pivotal and non-pivotal studies
  • Contribute to the preparation of study protocols, reports, and bioanalytical sections of regulatory submissions (e.g., IND, NDA, BLA) and address relevant queries from regulatory agencies (with the support of the Director, Preclinical ADME)


Candidate Profile:


Essential:


  • BSc, MSc or PhD in chemistry, analytical sciences, pharmaceutical sciences, or a related field
  • Experience in the pharmaceutical industry supporting bioanalysis in non-clinical and clinical studies
  • Experience developing and validating bioanalytical methods for small molecules
  • Strong knowledge in GLP/GCP regulations and regulatory guidance documents that apply to bioanalysis
  • Excellent written and oral communication skills
  • Demonstrated ability to work effectively in a matrix organization
  • Proven ability to prioritise and deploy resources appropriately to align with project and corporate objectives


Nice to have:


  • Experience preparing bioanalytical sections of regulatory submission documents (e.g., IND, NDA/BLA)
  • Experience in analytical chemistry
  • Working knowledge of biomarker assessment


【For NYC】Compensation Description (annually):


Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and work location.


Base pay is one part of the Total Package that is provided to compensate and recognise employees for their work and any role at Compass, regardless of the location, is eligible for additional discretionary bonuses and equity.


【Base salary per annum】:

$125,000—$190,000 USD


Benefits & Compensation:


For an overview of our benefits package and compensation information, please visit "Working at Compass".

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