VP of Drug Development

Remote (Sydney, New South Wales, Australia)

VP of Drug Development

Type: Full-time, Flexible

Location: Sydney, Australia, Flexible

Reports to: CEO

Start date: ASAP

Psylo is a biotech company developing therapeutics inspired by psychedelics found in nature. Our goal is to produce next-generation neuropsychiatric medications which are accessible to a broader patient population. See more about us here:

  • Psylo is based at the University of New South Wales and was recently named a Top 100 Innovator - https://www.theaustralian.com.au/business/top-innovators
  • Chief Scientist Sam Banister speaks with Hamilton Morris about medical chemistry and Psylo - https://www.youtube.com/watch?v=WZ0fcCTyvDU
  • CSIRO, Australia’s national health agency, collaborates with Psylo to evaluate neuroplasticity of novel psychedelic compounds - https://www.csiro.au/en/news/News-releases/2022/PSYLO-engages-CSIRO-to-evaluate-neuroplasticity-of-novel-psychedelic-compounds


Psylo is searching for a cross-functional biotech exec to help us navigate the transition to becoming a clinical company. The successful candidate will shape the direction of clinical candidate selection and IND enabling studies, and ensure the R&D program is operating with maximum efficiency.


Our team is located in Sydney, Australia on the University of NSW’s campus (10 minutes from the beach). Some of our work is together as an in-person team, however this role can be a hybrid position. A remote position will be considered.



  • Steer pipeline optimisation and clinical candidate selection from a commercial POV
  • Develop the Target Product Profile and narrow in on indication for clinical candidates
  • Maintain an up to date view of the competitive landscape, with a comprehensive understanding of key competitors' R&D programs
  • Own the regulatory approval process so we are one step ahead in our planning
  • Inform the financial modelling for reaching our various development milestones
  • Recruit and engage the appropriate advisors and consultants to progress Psylo’s program
  • Attract potential collaborators, partners, and investors to contribute to our development
  • Identify and drive successful grant applications and other funding opportunities


  • Provide oversight and guidance of in-house and outsourced R&D for lead candidates
  • Establish and maintain low-friction processes so the team is working together in lock step
  • Maintain positive commercial relationships with key research collaborators and partners
  • Coordinate the chemistry and pharmacology teams to drive smooth R&D handoffs
  • Work with CEO and finance team to ensure appropriate financial processes are in place
  • Train and/or mentor members of the internal teams as needed.



  • A track record of successful CNS drug development and commercialisation experience
  • A deep understanding of GPCR pharmacology, serotonin receptors, and neuropsychiatric disorders
  • Proven experience in regulatory strategy, design and execution
  • M.S/Ph.D. in a biomedical field, with 5-7 years of work experience in drug development
  • An international network of partners, collaborators, and advisors to draw upon


  • Attention to detail, with exceptional organisation and time management skills
  • Superb communication and collaboration skills with commercial and scientific coworkers
  • Comfort in working in a fast paced and ever-changing start-up environment
  • Ability to analyse and interpret data to provide unique insight to the business
  • Capable of working independently and as part of a multidisciplinary team

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